A cheap antidepressant reduced the need for hospitalization among high-risk adults with COVID-19 in a study hunting for existing drugs that could be repurposed to treat coronavirus.
Researchers tested the pill used for depression and obsessive-compulsive disorder because it was known to reduce inflammation and looked promising in smaller studies.
They’ve shared the results with the U.S. National Institutes of Health, which publishes treatment guidelines, and they hope for a World Health Organization recommendation.
“If WHO recommends this, you will see it widely taken up,” said study co-author Dr. Edward Mills of McMaster University in Hamilton, Ontario, adding that many poor nations have the drug readily available. “We hope it will lead to a lot of lives saved.”
The pill, called fluvoxamine, would cost $4 for a course of COVID-19 treatment. By comparison, antibody IV treatments cost about $2,000 and Merck’s experimental antiviral pill for COVID-19 is about $700 per course. Some experts predict various treatments eventually will be used in combination to fight the coronavirus.
Researchers tested the antidepressant in nearly 1,500 Brazilians recently infected with coronavirus who were at risk of severe illness because of other health problems, such as diabetes. About half took the antidepressant at home for 10 days, the rest got dummy pills. They were tracked for four weeks to see who landed in the hospital or spent extended time in an emergency room when hospitals were full.
In the group that took the drug, 11% needed hospitalization or an extended ER stay, compared to 16% of those on dummy pills.
The results, published Wednesday in the journal Lancet Global Health, were so strong that independent experts monitoring the study recommended stopping it early because the results were clear.
Questions remain about the best dosing, whether lower risk patients might also benefit and whether the pill should be combined with other treatments.
The larger project looked at eight existing drugs to see if they could work against the pandemic virus. The project is still testing a hepatitis drug, but all the others — including metformin, hydroxychloroquine, and ivermectin — haven’t panned out.
The cheap generic and Merck’s COVID-19 pill work in different ways and “may be complementary,” said Dr. Paul Sax of Brigham and Women’s Hospital and Harvard Medical School, who was not involved in the study. Earlier this month, Merck asked regulators in the U.S. and Europe to authorize its antiviral pill.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
Culled from Yahoo News
2 [url=https://store-parket.ru/category/inzhenernaja-doska/?yclid=1]инженерная доска [/url]
То, что ламинат, в отличие от паркета, является более гулким, тоже неверное высказывание [url=https://store-parket.ru/category/probkovoe-pokrytie/?yclid=1]пробковые [/url]
Это зависит от подложки и от того, насколько хорошо выровнено основание для пола [url=https://store-parket.ru/category/massivnaya-doska/?yclid=1]массивная паркетная доска [/url]
Ведь только добившись идеального прилегания покрытия к основанию, можно добиться минимальной гулкости [url=https://store-parket.ru/category/inzhenernaja-doska/?yclid=1]инженерный паркет [/url]
Применив пробковую подложку можно добиться более лучшего эффекта шумоизоляции [url=https://store-parket.ru/category/inzhenernaja-doska/?yclid=1]инженерная доска купить в москве [/url]
Тогда неважно, что сверху – паркет или ламинат – гулкости не будет [url=https://store-parket.ru/category/probkovoe-pokrytie/?yclid=1]купить пробку на пол [/url]
И наоборот [url=https://store-parket.ru/category/laminat/?yclid=1]дешевый ламинат купить [/url]
При нанесении лака трудно пропустить незакрашенный элемент, ведь лак сразу же после нанесения делает поверхность более насыщенной и яркой [url=https://store-parket.ru/category/massivnaya-doska/?yclid=1]массивная доска купить [/url]
Но все же нужно внимательно следить за точностью нанесения [url=https://store-parket.ru/category/laminat/?yclid=1]ламинат [/url]
Многих интересует вопрос, можно ли мыть паркетную доску, особенно если есть современный моющий пылесос, облегчающий процесс уборки [url=https://store-parket.ru/category/parketnaja-doska/?yclid=1]паркетная доска в москве [/url]
Ответ прост – не следует, поскольку влага, проникнув в структуру дерева, повредит ее [url=https://store-parket.ru/category/massivnaya-doska/?yclid=1]доска для пола массив [/url]
Для того, чтобы понять, какое из напольных покрытий предпочтительнее выбрать для конкретного помещения, необходимо сравнить их по основным параметрам — устойчивость к повреждениям, устойчивость к температуре и влажности, внешний вид, простота или сложность ухода и, наконец, цена [url=https://store-parket.ru/category/massivnaya-doska/?yclid=1]массив доски для пола [/url]
Перечислим подробно, из чего же состоит паркетная доска [url=https://store-parket.ru/category/massivnaya-doska/?yclid=1]доска массив [/url]
Начнем сверху [url=https://store-parket.ru/?yclid=1]Купить Пробковый Пол [/url]
Итак, для защиты от внешних воздействий верхним слоем (вернее, несколькими слоями) наносится специальный лак [url=https://store-parket.ru/category/laminat/?yclid=1]ламинированный пол [/url]
Если говорить про монтаж садового паркета, нельзя обойти вниманием некоторые особенности этого процесса [url=https://store-parket.ru/category/laminat/?yclid=1]самый дешевый ламинат [/url]
К примеру – подготовка основания [url=https://store-parket.ru/category/probkovoe-pokrytie/?yclid=1]пробковое дерево купить [/url]
Это очень важный этап, основа должна быть максимально плотной, при этом ровной [url=https://store-parket.ru/category/laminat/?yclid=1]стоимость ламината за 1 кв метр [/url]
[url=http://celebrex.guru/]celebrex 300[/url] [url=http://cialisytabs.monster/]best us price tadalafil[/url]
[url=http://albuterol.directory/]how to order albuterol tabs without a prescription[/url] [url=http://viagrattabs.monster/]australia viagra cost[/url] [url=http://cialisxtab.monster/]buy generic tadalafil online cheap[/url] [url=http://buygabapentin.store/]gabapentin 800 mg pill[/url] [url=http://cialisytab.monster/]purchase cialis online canada[/url] [url=http://albenza.shop/]albendazole 200 mg tablet[/url] [url=http://gabapentintab.online/]buy neurontin online uk[/url]
[url=http://levaquin.shop/]levaquin[/url]
[url=https://viagrabtabs.quest/]viagra in canada for sale[/url] [url=https://cialisitab.quest/]cheap cialis 60 mg[/url] [url=https://cialisstab.monster/]can you buy cialis otc[/url] [url=https://buypropranolol.shop/]proprnolol where to purchase[/url] [url=https://buycymbalta.digital/]cymbalta online pharmacy[/url] [url=https://viagraktabs.monster/]where to buy viagra pills[/url]
[url=https://anafranil.boutique/]anafranil prices[/url] [url=https://buyprednisone.digital/]prednisone 20 mg tablet[/url] [url=https://buybenicar.works/]benicar medicine[/url] [url=https://propranololtabs.online/]propranolol tablets 10 mg[/url] [url=https://albuterol.directory/]ventolin inhaler without prescription[/url]
[url=http://cialisytab.monster/]tadalafil 5mg coupon[/url]
[url=http://hydroxychloroquine.email/]hydroxychloroquine 200 mg tablet[/url]
[url=http://neurontintab.online/]medication neurontin 300 mg[/url] [url=http://buymodafinil.guru/]modafinil for sale online[/url]
[url=https://acyclovir.directory/]cheap acyclovir cream[/url] [url=https://benicar.guru/]benicar 20[/url] [url=https://buylisinopril.digital/]generic lisinopril 40 mg[/url] [url=https://buycymbalta.digital/]40 mg cymbalta[/url] [url=https://lexapro.works/]lexapro buy online india[/url] [url=https://buysynthroid.monster/]synthroid rx cost[/url] [url=https://prednisolone.guru/]prednisolone gel[/url] [url=https://cialisstab.monster/]tadalafil 30mg tablet[/url]
[url=https://cialisvtab.quest/]cialis 5 mg tablet[/url]
[url=http://clopidogrel.works/]order plavix[/url]
[url=http://buyprednisone.digital/]1.5 prednisone[/url]
[url=https://viagraktab.quest/]us online pharmacy viagra[/url] [url=https://buycelebrex.boutique/]celebrex 200 mg prices[/url] [url=https://buygabapentin.store/]gabapentin 500 mg capsules[/url] [url=https://buyfinasteride.works/]propecia generic online[/url] [url=https://viagrattabs.monster/]viagra cream uk[/url] [url=https://paroxetine.boutique/]buy paxil online[/url] [url=https://buyneurontin.boutique/]neurontin 100mg[/url]
[url=http://buyacyclovir.boutique/]cost prescription acyclovir[/url]
[url=http://propranololtabs.online/]where to buy propranolol australia[/url]
[url=https://valtrex.works/]valtrex generic[/url]
[url=http://paroxetine.boutique/]paxil tablet price[/url]
[url=http://celebrex.guru/]celebrex generic india[/url] [url=http://effexor.boutique/]order effexor xr[/url] [url=http://hydrochlorothiazide.boutique/]hydrochlorothiazide 12.5 mg brand[/url] [url=http://buypropecia.works/]online propecia usa[/url] [url=http://buylisinopril.digital/]prinivil generic[/url] [url=http://buysynthroid.monster/]0.05 mg synthroid[/url] [url=http://viagrabtabs.quest/]buy viagra pills canada[/url] [url=http://fluoxetine.digital/]prozac drug[/url]
[url=http://cialisitab.quest/]tadalafil 10 mg canada[/url]
[url=https://viagraktabs.monster/]viagra on the web[/url]
[url=https://silagra.guru/]silagra 50 mg tablet[/url]
[url=https://viagrautabs.monster/]female viagra in india[/url]
[url=http://pharmacy.golf/]web pharmacy[/url]
[url=http://buycelebrex.boutique/]celebrex 200mg where to buy[/url]
[url=http://viagraftabs.monster/]how to get female viagra pills[/url]
[url=https://acyclovir.directory/]zovirax tablets nz[/url]
[url=https://cialisatab.quest/]generic cialis nz[/url]
[url=https://buyatarax.works/]buy atarax 25mg[/url]
[url=http://canadianpharmacy.boutique/]safe online pharmacy[/url]
[url=http://effexor.fun/]generic effexor online[/url] [url=http://zoloft.fun/]zoloft tablets 250mg[/url] [url=http://cephalexin.works/]keflex generic price[/url] [url=http://chloroquine.boutique/]malaraquin[/url] [url=http://trazodone.site/]400 mg trazodone[/url]
[url=https://glucophage.fun/]buy metformin 500mg[/url] [url=https://retina.run/]where to buy retin a in canada[/url] [url=https://hydroxychloroquine.sbs/]hydroxychloroquine tablets 10 mg[/url] [url=https://drugstore.fun/]online pharmacy india[/url]
[url=http://metformin.fun/]metformin cost in usa[/url] [url=http://promethazine.site/]phenergan australia prescription[/url] [url=http://trazodone.loan/]desyrel generic[/url] [url=http://tizanidine.fun/]purchase zanaflex online[/url]
[url=https://hydrochlorothiazide.site/]hydrochlorothiazide 50 mg daily[/url]
[url=https://amoxicillin.business/]buy augmentin tab online no prescription[/url]
[url=http://fluconazole.xyz/]diflucan tablet[/url]
[url=https://antabuse.digital/]disulfiram cost in us[/url]
[url=https://drugstore.fun/]canadian pharmacy cialis[/url]
[url=http://acyclovir.sbs/]how much is acyclovir pills[/url]
[url=https://prednisolone.run/]buy prednisolone 5mg tablets uk[/url]
[url=https://anafranil.xyz/]anafranil 25[/url]
[url=https://mebendazolevermox.today/]vermox india[/url] [url=https://abilifyaripiprazole.quest/]abilify discount canada[/url] [url=https://zofran.works/]zofran otc mexico[/url] [url=https://prednisolone.store/]prednisolone 5mg capsules[/url] [url=https://tadacip.email/]buy tadacip in usa[/url] [url=https://azithromycin.guru/]cost of azithromycin 500 mg in india[/url]
[url=https://citalopram.fun/]citalopram hbr tabs[/url] [url=https://anafranil.xyz/]anafranil 50 mg[/url] [url=https://cleocin.fun/]600 mg clindamycin[/url] [url=https://sumycin.xyz/]tetracycline 100 mg[/url] [url=https://malegra.site/]malegra 100 tablet[/url] [url=https://vardenafil.men/]price of levitra in canada[/url]
[url=https://prazosin.shop/]prazosin 5[/url] [url=https://allopurinolp.com/]allopurinol generic cost[/url] [url=https://dutasteride.store/]avodart 0.4 mg[/url] [url=https://colchicine100.com/]colchicine 0.6 mg brand in india[/url] [url=https://aralen.us.com/]chloroquine usa[/url] [url=https://tretinoin.cyou/]tretinoin cream buy online mexico[/url] [url=https://amitriptylineelavil.quest/]elavil otc[/url]
[url=https://eng.18ps.ru/]ШґШ±Ш§ШЎ polimerpeschany ШШіЩ†Ш§[/url] – Ш§Щ„ШЁЩ„Ш§ШіШЄЩЉЩѓ Ш§Щ„Щ…Ш¬Ш§Ш±ЩЉ Ш§Щ„ШЁЩ€Ш§ШЁШ§ШЄ Щ„ШґШ±Ш§ШЎ, Ш§Ш¶ШєШ· db2432 ШґШ±Ш§ШЎ
[url=https://zoloft.business/]how to get zoloft prescription online[/url]
[url=http://vardenafil.men/]cheap levitra australia[/url]
[url=https://promethazine.site/]order phenergan without prescription[/url]